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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Primate (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot (Negative)

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

Product Specifications

Immunogen

The immunogen for this product maps to a region between residue 655 and 705 of human Lethal (3) Malignant Brain Tumor-Like 2 using the numbering given in entry NP_113676.2 (GeneID 83746).

Reactivity Notes

Orangutan (100%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for L3MBTL2 Antibody

Immunohistochemistry-Paraffin: L3MBTL2 Antibody [NBP1-49965]

Immunohistochemistry-Paraffin: L3MBTL2 Antibody [NBP1-49965]

Immunohistochemistry-Paraffin: L3MBTL2 Antibody [NBP1-49965] - Human ovarian carcinoma. Antibody: Affinity purified rabbit anti-L3MBTL2 used at a dilution of 1:1,000 (1ug/ml). Detection: Vector ImmPACT NovaRED
Immunoprecipitation: L3MBTL2 Antibody [NBP1-49965]

Immunoprecipitation: L3MBTL2 Antibody [NBP1-49965]

Immunoprecipitation: L3MBTL2 Antibody [NBP1-49965] - Detection of Human L3MBTL2 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-L3MBTL2 antibody used for IP at 3 mcg/mg lysate. L3MBTL2 was also immunoprecipitated by rabbit anti-L3MBTL2 antibody which recognizes an upstream epitope. For blotting immunoprecipitated L3MBTL2 was used at 1 mcg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Applications for L3MBTL2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:5000

Immunohistochemistry-Paraffin

1:10-1:500

Immunoprecipitation

2-5 ug/mg lysate
Application Notes
Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: L3MBTL2

Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes,probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with achromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell intomitosis

Alternate Names

dJ756G23.3, DKFZP761I141, H-l(3)mbt-l, H-l(3)mbt-like protein 2, l(3)mbt-like 2 (Drosophila), L(3)mbt-like protein 2, L3MBT, lethal(3)malignant brain tumor-like protein 2

Gene Symbol

L3MBTL2

Additional L3MBTL2 Products

Product Documents for L3MBTL2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for L3MBTL2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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