Lactoperoxidase Antibody (15#)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-41574

Novus Biologicals, part of Bio-Techne
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NBP3-41574
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Key Product Details

Species Reactivity

Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 15#

Concentration

1 mg/ml

View all Lactoperoxidase Antibodies »

Product Specifications

Immunogen

Immunized with recombinant Rat Lactoperoxidase (Uniprot#: D4A400; Pro351-Glu589 (Uniprot#: D4A400)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Applications for Lactoperoxidase Antibody (15#)

Application
Recommended Usage

ELISA

0.05-2ug/ml

Immunocytochemistry/ Immunofluorescence

5-30ug/ml

Immunohistochemistry-Frozen

5-30ug/ml

Immunohistochemistry-Paraffin

5-30ug/ml

Western Blot

0.5-5ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS, pH7.4, 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Lactoperoxidase

Lactoperoxidase is an antibacterial agent in cow milk. The heme protein lactoperoxidase (LPO), also referred to as salivary peroxidase (SPO), is an oxidoreductase secreted into milk. LPO belongs to the XPO subfamily of the peroxidase family. It is expressed in mammary and salivary glands, and in the presence of H2O2, LPO acts as a catalyst for the oxidation of many phenols and aromatic amines. It is crucial for protecting the lactating mammary gland and intestinal tract of newborn infants against microorganisms. LPO binds one calcium ion per heterodimer and one heme B (iron-protoporphyrin IX) group covalently per heterodimer. The LPO gene, which spans 28 kb, is similar in gene organization and sequence to the peroxidase genes MPO and EPX, suggesting the possibility that these genes evolved from a common ancestral gene. The LPO and MPO genes are arranged in a tail-to-tail manner on chromosome 17q23.1.

Alternate Names

EC 1.11.1, lactoperoxidase, MGC129990, MGC129991, Salivary peroxidase, SAPX, SPOEC 1.11.1.7

Gene Symbol

LPO

Additional Lactoperoxidase Products

Product Documents for Lactoperoxidase Antibody (15#)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Lactoperoxidase Antibody (15#)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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