Lambda Light Chain Antibody (K22-Y)

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-30142

Recombinant Monoclonal Antibody.
Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # K22-Y

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Lambda Light Chain Antibodies »

Product Summary for Lambda Light Chain Antibody (K22-Y)

Immunogen

Peptide derived from N-terminal sequence of human lambda light chain IgG. Antibody recognizes the epitope between Ala50 - Ser68.

Specificity

This antibody is specific for the N terminus of the lambda light chain.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody is immunoaffinity purified with immunogenic peptide as a ligand.

Scientific Data Images for Lambda Light Chain Antibody (K22-Y)

Immunohistochemistry-Paraffin: Lambda Light Chain Antibody (K22-Y) [NBP1-30142]

Immunohistochemistry-Paraffin: Lambda Light Chain Antibody (K22-Y) [NBP1-30142]

Immunohistochemistry-Paraffin: Human lambda light chain Antibody (K22-Y) [NBP1-30142] - Formalin fixed, paraffin embedded human tissues (4 um sections) stained with anti - Human Lambda light chain (DB 039) monospecific clonal antibody.
Immunohistochemistry-Paraffin: Lambda Light Chain Antibody (K22-Y) [NBP1-30142]

Immunohistochemistry-Paraffin: Lambda Light Chain Antibody (K22-Y) [NBP1-30142]

Immunohistochemistry-Paraffin: Human lambda light chain Antibody (K22-Y) [NBP1-30142] - Human lambda light chain Antibody (K22-Y) human tonsil tissue stained with anti-Human Lambda Light Chain antibody.
Immunohistochemistry-Paraffin: Lambda Light Chain Antibody (K22-Y) [NBP1-30142]

Immunohistochemistry-Paraffin: Lambda Light Chain Antibody (K22-Y) [NBP1-30142]

Immunohistochemistry-Paraffin: Human lambda light chain Antibody (K22-Y) [NBP1-30142] - Formalin fixed, paraffin embedded human tissues (4 um sections) stained with anti - Human Lambda light chain (DB 039) monospecific clonal antibody.

Applications for Lambda Light Chain Antibody (K22-Y)

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:100-1:500
Application Notes
For use in Immunohistochemistry frozen and paraffin embedded sections. For 0.1ml, 0.5ml and 1.0ml sizes, use recommended dilutions. For 7.0ml and 15.0ml sizes, products should be used undiluted.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

20mM Tris/HCl (pH 8.0) and 20 mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Lambda Light Chain

All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30 , the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain are present in serum (kappa, 1.6-15.2 mg/L; Lambda, 0.4-4.2mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins).

Alternate Names

IGLC, immunoglobulin lambda constant group

Gene Symbol

IGLC1

UniProt

P01842 (Human)

Additional Lambda Light Chain Products

Product Documents for Lambda Light Chain Antibody (K22-Y)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Lambda Light Chain Antibody (K22-Y)

This antibody is immunoaffinity purified with immunogenic peptide as a ligand.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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