Lamin A + C Antibody (S06-7H5)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19963

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19963-100ul
NBP3-19963-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S06-7H5

Concentration

0.3 mg/ml

View all Lamin A + C Antibodies »

Product Summary for Lamin A + C Antibody (S06-7H5)

Immunogen

A synthetic peptide of human Lamin A + C (Uniprot # P02545)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Lamin A + C Antibody (S06-7H5)

Western Blot: Lamin A + C Antibody (S06-7H5) [NBP3-19963]

Western Blot: Lamin A + C Antibody (S06-7H5) [NBP3-19963]

Western Blot: Lamin A + C Antibody (S06-7H5) [NBP3-19963] - Western blot detection of Lamin A + C in 3T3, Hela cell lysates using NBP3-19963 (1:1000 diluted). Predicted band size: 74kDa. Observed band size: 74, 63kDa.
Immunocytochemistry/ Immunofluorescence: Lamin A + C Antibody (S06-7H5) [NBP3-19963]

Immunocytochemistry/ Immunofluorescence: Lamin A + C Antibody (S06-7H5) [NBP3-19963]

Immunocytochemistry/Immunofluorescence: Lamin A + C Antibody (S06-7H5) [NBP3-19963] - Immunofluorescence of Lamin A + C (green) in Hela cells using NBP3-19963 at dilution 1/50, and DAPI (blue)
Immunohistochemistry-Paraffin: Lamin A + C Antibody (S06-7H5) [NBP3-19963]

Immunohistochemistry-Paraffin: Lamin A + C Antibody (S06-7H5) [NBP3-19963]

Immunohistochemistry-Paraffin: Lamin A + C Antibody (S06-7H5) [NBP3-19963] - Immunohistochemistry of Lamin A + C in paraffin-embedded Human breast cancer tissue using NBP3-19963 at dilution 1/5

Applications for Lamin A + C Antibody (S06-7H5)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1/20

Immunohistochemistry

1/20

Western Blot

1/1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Lamin A + C

Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope. These proteins are found in many different cell types in three different forms (A, B, and C). Lamins A and C are alternatively spliced versions of the LMNA gene. The LMNA gene has been linked to many disorders of the muscular system, nervous system, and the fat distributions systems including: Emery-Dreifuss muscular dystrophy, Dunnigan-type familial partial lipodystrophy (FPLD), limb-girdle muscular dystrophy (LGMD1B), dilated cardiomyopathy (CMD1A), axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1), and mandibuloacral dysplasia (MAD).

Alternate Names

CDCD1, CDDC, CMD1A, CMT2B1, dilated 1A (autosomal dominant), EMD2, FPLD, HGPSFPL, lamin A/C, lamin A/C-like 1, lamin-A/C, LDP1, LFP, LGMD1B, limb girdle muscular dystrophy 1B (autosomal dominant), LMN1IDC, LMNC, LMNL1, prelamin-A/C, PRO1,70 kDa lamin, progeria 1 (Hutchinson-Gilford type), renal carcinoma antigen NY-REN-32

Gene Symbol

LMNA

Additional Lamin A + C Products

Product Documents for Lamin A + C Antibody (S06-7H5)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Lamin A + C Antibody (S06-7H5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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