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LAMTOR1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89909

Novus Biologicals, part of Bio-Techne
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NBP1-89909
NBP1-89909-25ul

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (99%), Rat (97%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: NEDSDQDREERKLLLDPSSPPTKALNGAEPNYHSLPSARTDEQALLSSILAKTASNIIDVSAADSQGMEQHEYMDRARQYSTRLAVLSSSLTHWKKLPPLPSLTSQPHQVLASEPIPFSDLQQVSRIAAYAYSALSQIRVDAKEELVV

Reactivity Notes

Reactivity reported in scientific literature (PMID: 22576015)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LAMTOR1 Antibody

Immunohistochemistry-Paraffin: LAMTOR1 Antibody [NBP1-89909]

Immunohistochemistry-Paraffin: LAMTOR1 Antibody [NBP1-89909]

Immunohistochemistry-Paraffin: LAMTOR1 Antibody [NBP1-89909] - Staining of human prostate shows strong granular cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: LAMTOR1 Antibody [NBP1-89909]

Immunohistochemistry-Paraffin: LAMTOR1 Antibody [NBP1-89909]

Immunohistochemistry-Paraffin: LAMTOR1 Antibody [NBP1-89909] - Staining of human duodenum shows strong granular cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: LAMTOR1 Antibody [NBP1-89909]

Immunohistochemistry-Paraffin: LAMTOR1 Antibody [NBP1-89909]

Immunohistochemistry-Paraffin: LAMTOR1 Antibody [NBP1-89909] - Staining of human pancreas shows strong granular cytoplasmic positivity in exocrine glandular cells.

Applications for LAMTOR1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF reactivity reported in (PMID: 30428163).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LAMTOR1

Activates RHOA. Binds to CDKN1B and prevents interaction of CDKN1B and RHOA. This leaves RHOA in a form accessible to ARHGEF2, thereby promoting ARHGEF2-mediated exchange of GDP for GTP

Alternate Names

c11orf59, chromosome 11 open reading frame 59, FLJ20625, LAMTOR1, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1, late endosomal/lysosomal adaptor, MAPK and MTOR activator 1, Lipid raft adaptor protein p18, p18, p27kip1 releasing factor from RhoA, p27Kip1-releasing factor from RhoA, p27RF-RhoC11orf59, PDRO, PDROPdro, Protein associated with DRMs and endosomes, ragulator complex protein PDRO, Ragulator1, RhoA activator C11orf59

Gene Symbol

LAMTOR1

Additional LAMTOR1 Products

Product Documents for LAMTOR1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for LAMTOR1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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