Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot (Negative)

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all LAP1B Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 275 and 325 of human lamina associated polypeptide 1B using the numbering given in entry NP_056417.2 (GeneID 26092).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LAP1B Antibody

Immunohistochemistry: LAP1B Antibody [NBP1-19123]

Immunohistochemistry: LAP1B Antibody [NBP1-19123]

Immunohistochemistry: LAP1B Antibody [NBP1-19123] - Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-LAP1B used at a dilution of 1:200 (1ug/ml). Detection: DAB
Immunoprecipitation: LAP1B Antibody [NBP1-19123]

Immunoprecipitation: LAP1B Antibody [NBP1-19123]

Immunoprecipitation: LAP1B Antibody [NBP1-19123] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Affinity purified rabbit anti-LAP1B antibody used for IP at 3 mcg/mg lysate. LAP1B was also immunoprecipitated by rabbit anti- LAP1B antibody NBP1-19122, which recognizes an upstream epitope.

Applications for LAP1B Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Immunoprecipitation

2-5 ug/mg lysate
Application Notes
It is not recommended for western analysis.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: LAP1B

Lamina-associated polypeptide 1B (LAPB1) binds to A- and B-type lamins. It is a single-pass membrane protein that localizes to the inner membrane of the nucleus and may play a role in membrane attachment and the assembly of the nuclear lamina. LAPB1 is also called torsin-1A-interacting protein 1 (TOR1AIP1) due to its association with torsin, an ATPase of the AAA- (adenosine triphosphatases associated with diverse cellular activities) family of proteins.

Alternate Names

DKFZp586G011, FLJ13142, lamina associated polypeptide 1B, lamina-associated polypeptide 1B, LAP1B, MGC3413, torsin A interacting protein 1, torsin-1A-interacting protein 1

Entrez Gene IDs

26092 (Human)

Gene Symbol

TOR1AIP1

UniProt

NP_056417.2 (Human)

Additional LAP1B Products

Product Documents for LAP1B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for LAP1B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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