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LAP1B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-47403

Novus Biologicals, part of Bio-Techne
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NBP2-47403
NBP2-47403-25ul

Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: EATSVQQKVNFSEEGETEEDDQDSSHSSVTTVKARSRDSDESGDKTTRSSSQYIESFWQSSQSQNFTAHDKQRSVLSSGYQKTPQEWAPQTARIRTRMQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LAP1B Antibody

Immunohistochemistry-Paraffin: LAP1B Antibody [NBP2-47403]

Immunohistochemistry-Paraffin: LAP1B Antibody [NBP2-47403]

Immunohistochemistry-Paraffin: LAP1B Antibody [NBP2-47403] - Staining of human cerebral cortex, kidney, lymph node and testis using Anti-TOR1AIP1 antibody NBP2-47403 (A) shows similar protein distribution across tissues to independent antibody NBP2-47402 (B).
Western Blot: LAP1B Antibody [NBP2-47403]

Western Blot: LAP1B Antibody [NBP2-47403]

Western Blot: LAP1B Antibody [NBP2-47403] - Analysis using Anti-TOR1AIP1 antibody NBP2-47403 (A) shows similar pattern to independent antibody NBP2-47402 (B).
Immunocytochemistry/ Immunofluorescence: LAP1B Antibody [NBP2-47403]

Immunocytochemistry/ Immunofluorescence: LAP1B Antibody [NBP2-47403]

Immunocytochemistry/Immunofluorescence: LAP1B Antibody [NBP2-47403] - Staining of human cell line MCF7 shows localization to nuclear membrane. Antibody staining is shown in green.

Applications for LAP1B Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LAP1B

Lamina-associated polypeptide 1B (LAPB1) binds to A- and B-type lamins. It is a single-pass membrane protein that localizes to the inner membrane of the nucleus and may play a role in membrane attachment and the assembly of the nuclear lamina. LAPB1 is also called torsin-1A-interacting protein 1 (TOR1AIP1) due to its association with torsin, an ATPase of the AAA- (adenosine triphosphatases associated with diverse cellular activities) family of proteins.

Alternate Names

DKFZp586G011, FLJ13142, lamina associated polypeptide 1B, lamina-associated polypeptide 1B, LAP1B, MGC3413, torsin A interacting protein 1, torsin-1A-interacting protein 1

Gene Symbol

TOR1AIP1

Additional LAP1B Products

Product Documents for LAP1B Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for LAP1B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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