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LAR/PTPRF Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81325

Novus Biologicals, part of Bio-Techne
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NBP1-81325
NBP1-81325-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (90%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for LAR/PTPRF Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: WHPPKELPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LAR/PTPRF Antibody

Immunocytochemistry/ Immunofluorescence: LAR/PTPRF Antibody [NBP1-81325]

Immunocytochemistry/ Immunofluorescence: LAR/PTPRF Antibody [NBP1-81325]

Immunocytochemistry/Immunofluorescence: LAR/PTPRF Antibody [NBP1-81325] - Staining of human cell line A-431 shows localization to the Golgi apparatus. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: LAR/PTPRF Antibody [NBP1-81325]

Immunohistochemistry-Paraffin: LAR/PTPRF Antibody [NBP1-81325]

Immunohistochemistry-Paraffin: LAR/PTPRF Antibody [NBP1-81325] - Staining of human small intestine shows strong cytoplasmic and membranous positivity, with a granular pattern in glandular cells.

Applications for LAR/PTPRF Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LAR

PTPRF, also known as Receptor-type tyrosine-protein phosphatase F, is a 213kDa 1907 amino acid protein with a shorter 212kDa 1898 isoform. PTPRF is a member of the protein tyrosine phosphatase (PTP) family and functions as a possible cell adhesion receptor. Research is being conducted on PTPRF in relation to melanoma, carcinoma, retinitis, thyroid carcinoma, ureterocele, lung cancer, breast cancer and obesity. PTPRF is linked to the cell adhesion and insulin signaling pathways where it interacts with CAV1, PRPF40A, SKIL, ZNF512B and JUP.

Long Name

Leukocyte Antigen-Related Tyrosine Phosphatase

Alternate Names

PTPRF

Entrez Gene IDs

5792 (Human)

Gene Symbol

PTPRF

UniProt

Additional LAR Products

Product Documents for LAR/PTPRF Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for LAR/PTPRF Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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