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Latent TGF-beta bp4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-43671

Novus Biologicals, part of Bio-Techne
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NBP2-43671

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Rat (97%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the N-terminus region of human Latent TGF-beta bp4. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

173 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Latent TGF-beta bp4 Antibody

Western Blot: Latent TGF-beta bp4 Antibody [NBP2-43671]

Western Blot: Latent TGF-beta bp4 Antibody [NBP2-43671]

Western Blot: Latent TGF-beta bp4 Antibody [NBP2-43671] - LTBP4 antibody detects LTBP4 protein by Western blot analysis. Mouse tissue extracts (50 ug) was separated by 5% SDS-PAGE, and the membrane was blotted with LTBP4 antibody diluted at 1:500.
Immunocytochemistry/ Immunofluorescence: Latent TGF-beta bp4 Antibody [NBP2-43671]

Immunocytochemistry/ Immunofluorescence: Latent TGF-beta bp4 Antibody [NBP2-43671]

Immunocytochemistry/Immunofluorescence: Latent TGF-beta bp4 Antibody [NBP2-43671] - Analysis of methanol-fixed A431, using LTBP4 antibody at 1:200 dilution.
Immunohistochemistry-Paraffin: Latent TGF-beta bp4 Antibody [NBP2-43671]

Immunohistochemistry-Paraffin: Latent TGF-beta bp4 Antibody [NBP2-43671]

Immunohistochemistry-Paraffin: Latent TGF-beta bp4 Antibody [NBP2-43671] - Analysis of Adrenal Gland Tumor. LTBP4 antibody [N1N2], N-term dilution: 1:250.

Applications for Latent TGF-beta bp4 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS, 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Latent TGF-beta bp4

Transforming growth factor-beta, or TGFB (see TGFB1; MIM 190180), remains biologically latent after secretion, blocked from activity by its N-terminal propeptide (the latency-associated peptide, or LAP). TGFB is activated by its dissociation from LAP. The latent form of TGFB is secreted in association with a latent TGFB-binding protein, or LTBP (see LTBP1; MIM 150390), and assembled into the extracellular matrix. LTBPs are mainly composed of epidermal growth factor (EGF; MIM 131530)-like repeats and protein domains with 8-cysteine repeats, both of which are also found in fibrillins (e.g., MIM 134797). See Oklu and Hesketh (2000) (PubMed 11104663) for a review of the LTBP gene family.(supplied by OMIM)

Alternate Names

Latent TGFbeta bp4, LTBP-4, LTBP4

Gene Symbol

LTBP4

Additional Latent TGF-beta bp4 Products

Product Documents for Latent TGF-beta bp4 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Latent TGF-beta bp4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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