LEM3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57961

Novus Biologicals, part of Bio-Techne
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NBP2-57961
NBP2-57961-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all LEM3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: STVSDLELLKGLRALGENPHPITPFTRQLYHQQLEEAQIAPGPEFSGHSLELAAALRTGCIPDVQADEDALAQQFEQPDP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LEM3 Antibody

Immunohistochemistry-Paraffin: LEM3 Antibody [NBP2-57961]

Immunohistochemistry-Paraffin: LEM3 Antibody [NBP2-57961]

Immunohistochemistry-Paraffin: LEM3 Antibody [NBP2-57961] - Immunohistochemical staining of human bone marrow shows moderate cytoplasmic positivity in hematopoietic cells.

Applications for LEM3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LEM3

The LEM3 (ANKLE1) gene encodes an ankyrin repeat and LEM domain-containing protein 1 that in isoform 1 is 615 amino acids long, 66 kDA and in isoform 2 is 575 amino acids long at 62 kDA. LEM3 interacts with the SUMO1, UBC, and RASSF5 genes. It has been linked to diseases such as breast cancer, venous insufficiency, ovarian Cancer, hepatitis b, and legionnaires' disease.

Alternate Names

ANKRD41, ankyrin repeat and LEM domain containing 1, ankyrin repeat and LEM domain-containing protein 1, FLJ39369, LEM domain containing 6, LEMD6, LEM-domain containing protein 3

Gene Symbol

ANKLE1

Additional LEM3 Products

Product Documents for LEM3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for LEM3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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