Lewis Y Antibody (A70-A/A9) [PE/Cy7]
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-54561PECY7
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Human
Applications
CyTOF-ready, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin
Label
PE/Cy7 (Excitation = 488 nm, Emission = 778 nm)
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # A70-A/A9
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Live Ls174T cells (human colon carcinoma cell line)
Epitope
(Fucalpha1-2Galbeta1-4/3[Fucalpha1-3/4]GlcNAcbeta-
Localization
Cell membrane, cytoplasmic and extracellular
Specificity
This antibody recognizes a carbohydrate epitope present on tumor-associated Lewis Y antigen (Fucalpha1-2Galbeta1-4/3[Fucalpha1-3/4]GlcNAcbeta-). Lewis Y is expressed in large bowel tumors and colorectal carcinomas. It may be useful in the classification of human renal and bladder tumors. The Lewis Y antigen has been evaluated as a clinical marker for the diagnosis and prognosis of cholangiocarcinoma, hepatocellular carcinoma and breast cancer.
Marker
Tumor Marker
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Applications for Lewis Y Antibody (A70-A/A9) [PE/Cy7]
Application
Recommended Usage
CyTOF-ready
Optimal dilutions of this antibody should be experimentally determined.
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
PBS
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark. Do not freeze.
Background: Lewis Y
Alternate Names
IPCA-2, IPCA6, IPCA-6, IPCA-8, PCANAP2, PCANAP6, PCANAP8, Prostate cancer-associated protein 6, PRST, Solute carrier family 45 member 3
Additional Lewis Y Products
Product Documents for Lewis Y Antibody (A70-A/A9) [PE/Cy7]
Product Specific Notices for Lewis Y Antibody (A70-A/A9) [PE/Cy7]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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