Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all LGI1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 13 amino acid synthetic peptide from near the amino terminus of human LGI1. The immunogen is located within the first 50 amino acids of LGI1. Amino Acid Squence: LLLTEGKKPAKPK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Lgi1 Antibody - BSA Free

Western Blot: Lgi1 AntibodyBSA Free [NBP1-76379]

Western Blot: Lgi1 AntibodyBSA Free [NBP1-76379]

Western Blot: Lgi1 Antibody [NBP1-76379] - Mouse brain tissue lysate with LGI1 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.

Applications for Lgi1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LGI1

The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist, but the top band seen in the western blot is likely to be non-specific. This LGI1 antibody is predicted to be specific to LGI1 and not recognize other LGI proteins.

Long Name

Leucine-Rich Glioma-Inactivated Protein 1

Alternate Names

ADLTE, ADPAEF, ADPEAF, BB130740, Epitempin, Epitempin-1, EPT, ETL1, IB1099

Gene Symbol

LGI1

UniProt

AAQ89244 (Human)

Additional LGI1 Products

Product Documents for Lgi1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Lgi1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.