Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all LGI2 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 10 amino acid synthetic peptide from near the center of human LGI2. The immunogen is located within amino acids 290 - 340 of LGI2. Amino Acid Squence: IYKYDESWTK

Specificity

This LGI2 antibody is predicted to be specific to LGI2 and not recognize other LGI proteins.Three isoforms of LGI2 are known to exist; this LGI2 antibody will recognize only the longest.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LGI2 Antibody - BSA Free

Western Blot: LGI2 AntibodyBSA Free [NBP1-76886]

Western Blot: LGI2 AntibodyBSA Free [NBP1-76886]

Western Blot: LGI2 Antibody [NBP1-76886] - Mouse liver tissue lysate with LGI2 antibody at (A) 1 and (B) 2 ug/ml.
LGI2 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: LGI2 Antibody - BSA Free [NBP1-76886] -

Immunocytochemistry/ Immunofluorescence: LGI2 Antibody - BSA Free [NBP1-76886] - Immunofluorescence of LGI2 in Human Brain cells with LGI2 antibody at 5 ug/mL.
LGI2 Antibody - BSA Free

Immunohistochemistry: LGI2 Antibody - BSA Free [NBP1-76886] -

Immunohistochemistry: LGI2 Antibody - BSA Free [NBP1-76886] - Immunohistochemical staining of human brain tissue using LGI2 antibody at 2.5 ug/mL.

Applications for LGI2 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

5 ug/mL

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LGI2

The leucine-rich, glioma inactivated gene 2 (LGI2) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI2 have not been found to be associated with ADTLE. Three isoforms of LGI2 are known to exist; this LGI2 antibody will recognize only the longest. This LGI2 antibody is predicted to be specific to LGI2 and not recognize other LGI proteins.

Long Name

Leucine-rich, Glioma-inactivated 2

Alternate Names

LGIL2

Gene Symbol

LGI2

UniProt

Q8K4Z0 (Mouse)

Additional LGI2 Products

Product Documents for LGI2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for LGI2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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