Liprin alpha 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-75291

Novus Biologicals, part of Bio-Techne
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NB100-75291
NB100-75291-0.025mg
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Chicken

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Liprin alpha 1 Antibodies »

Product Specifications

Immunogen

The immunogen for this antibody was a sequence from 310a.a. to 360a.a. from Liprin-alpha-1(a 1202a.a. long protein)

Reactivity Notes

This antibody is reactive against Human, mouse, rat.

Localization

Cytoplasm. Colocalizes with PTPRF at the ends of focal adhesions most proximal to the cell nucleus.

Specificity

Liprin-alpha-1

Clonality

Polyclonal

Host

Chicken

Applications for Liprin alpha 1 Antibody

Application
Recommended Usage

Western Blot

1:200- 1:500
Application Notes
Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Liprin alpha 1

Liprin alpha 1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane. possibly regulating their interaction with the extracellular environment and their association with substrates.

Alternate Names

FLJ42630, FLJ43474, LAR-interacting protein 1, LIP.1, LIP-1, LIP1FLJ41337, LIPRIN, Liprin-alpha1, liprin-alpha-1, MGC26800, Protein tyrosine phosphatase receptor type f polypeptide-interacting proteinalpha-1, protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interactingprotein (liprin), alpha 1, PTPRF-interacting protein alpha-1

Entrez Gene IDs

8500 (Human); 233977 (Mouse); 293645 (Rat)

Gene Symbol

PPFIA1

UniProt

Q13136 (Human)

Additional Liprin alpha 1 Products

Product Documents for Liprin alpha 1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Liprin alpha 1 Antibody

Chicken products cannot be exported to Canada.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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