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LIR-8/CD85c/LILRB5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-19352

Novus Biologicals, part of Bio-Techne
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NBP2-19352

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Chimpanzee (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human LIR-8/CD85c/LILRB5. The exact sequence is proprietary.

Localization

Membrane; Single-pass type I membrane protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

64 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for LIR-8/CD85c/LILRB5 Antibody

Western Blot: LIR-8/CD85c/LILRB5 Antibody [NBP2-19352]

Western Blot: LIR-8/CD85c/LILRB5 Antibody [NBP2-19352]

Western Blot: LIR-8/CD85c/LILRB5 Antibody [NBP2-19352] - Sample (30 ug of whole cell lysate) A: K562 7. 5% SDS PAGE gel, diluted at 1:1000.
Immunohistochemistry-Paraffin: LIR-8/CD85c/LILRB5 Antibody [NBP2-19352]

Immunohistochemistry-Paraffin: LIR-8/CD85c/LILRB5 Antibody [NBP2-19352]

Immunohistochemistry-Paraffin: LIR-8/CD85c/LILRB5 Antibody [NBP2-19352] - Human breast carcinoma. LILRB5 antibody [N2C1], Internal dilution: 1:250. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.

Applications for LIR-8/CD85c/LILRB5 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: LILRB5/CD85c/LIR-8

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Long Name

Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM And ITIM Domains), Member 5

Alternate Names

CD85c, LIR-8, LIR8

Gene Symbol

LILRB5

UniProt

Additional LILRB5/CD85c/LIR-8 Products

Product Documents for LIR-8/CD85c/LILRB5 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for LIR-8/CD85c/LILRB5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.