Key Product Details

Species Reactivity

Human, Mouse

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all LIV-1/Zip6 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide near the center of human ZIP6. The immunogen is located within amino acids 430 - 480 of ZIP6. Amino Acid Squence: FKDKKKKNQKKPENDD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LIV-1/Zip6 Antibody - BSA Free

Western Blot: LIV-1/Zip6 AntibodyBSA Free [NBP1-76503]

Western Blot: LIV-1/Zip6 AntibodyBSA Free [NBP1-76503]

Western Blot: LIV-1/Zip6 Antibody [NBP1-76503] - Mouse lung tissue lysate with LIV-1/Zip6 antibody at 1 ug/mL.
Immunohistochemistry-Paraffin: LIV-1/Zip6 Antibody - BSA Free [NBP1-76503]

Immunohistochemistry-Paraffin: LIV-1/Zip6 Antibody - BSA Free [NBP1-76503]

Immunohistochemistry-Paraffin: LIV-1/Zip6 Antibody [NBP1-76503] - Mouse lung tissue with ZIP6 antibody at 5 ug/mL.
LIV-1/Zip6 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: LIV-1/Zip6 Antibody - BSA Free [NBP1-76503] -

Immunocytochemistry/ Immunofluorescence: LIV-1/Zip6 Antibody - BSA Free [NBP1-76503] - Immunofluorescence of LIV-1/Zip6 in mouse lung tissue with LIV-1/Zip6 antibody at 20 u/mL.

Applications for LIV-1/Zip6 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LIV-1/Zip6

The zinc transporter ZIP6, also known as SLC39A6, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP6 was initially identified as LIV-1, an estrogen-regulated gene that has been implicated in metastatic breast cancer. Elevated ZIP6 expression has also been reported in human cervical cancer and the HeLa cell line; down-regulation of ZIP6 expression in HeLa by RNAi inhibited cell proliferation, colony formation, migration and invasiveness, as well as decreasing Snail and Slug levels, suggesting ZIP6 plays a regulatory role on the ERK1/2-Snail/Slug pathway.

Alternate Names

LIV-1, solute carrier family 39 (zinc transporter), member 6, zinc transporter ZIP6

Gene Symbol

SLC39A6

UniProt

NP_001092876 (Human)

Additional LIV-1/Zip6 Products

Product Documents for LIV-1/Zip6 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for LIV-1/Zip6 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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