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Livin Antibody (OTI1D12)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-02177

Novus Biologicals, part of Bio-Techne
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NBP2-02177
Conjugate
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI1D12

Concentration

0.36 mg/ml

Product Specifications

Immunogen

Full length human recombinant protein of human BIRC7 (NP_071444) produced in HEK293T cell.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

32.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Livin Antibody (OTI1D12)

Western Blot: Livin Antibody (OTI1D12) [NBP2-02177]

Western Blot: Livin Antibody (OTI1D12) [NBP2-02177]

Western Blot: Livin Antibody (1D12) [NBP2-02177] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Livin (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-Livin.
Immunohistochemistry-Paraffin: Livin Antibody (1D12) [NBP2-02177] Staining of paraffin-embedded liver tissue using anti-Livin mouse monoclonal antibody.
Flow Cytometry: Livin Antibody (OTI1D12) [NBP2-02177]

Flow Cytometry: Livin Antibody (OTI1D12) [NBP2-02177]

Flow Cytometry: Livin Antibody (1D12) [NBP2-02177] - Analysis of Jurkat cells, using anti-Livin antibody, (Red) compared to a nonspecific negative control antibody (Blue).

Applications for Livin Antibody (OTI1D12)

Application
Recommended Usage

Flow Cytometry

1:100

Immunohistochemistry

1:50

Immunohistochemistry-Paraffin

1:50

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

0.36 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Livin

The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.

Alternate Names

BIRC7, KIAP, ML-IAP

Entrez Gene IDs

79444 (Human)

Gene Symbol

BIRC7

Additional Livin Products

Product Documents for Livin Antibody (OTI1D12)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Livin Antibody (OTI1D12)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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