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LMTK2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89320

Novus Biologicals, part of Bio-Techne
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NBP1-89320
NBP1-89320-25ul

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: MELNGVQADFKPATLSSSLDNPKESVITGHFEKEKPRKIFDSEPLCLSDNLMHQDNFDPLNVQELSENFLFLQEKNLLKGSLSSKEHINDLQTELKNAGFTEAMLETSCRNSLDTELQFAENKPGLSLLQENV

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 26008968).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LMTK2 Antibody

Immunocytochemistry/ Immunofluorescence: LMTK2 Antibody [NBP1-89320]

Immunocytochemistry/ Immunofluorescence: LMTK2 Antibody [NBP1-89320]

Immunocytochemistry/Immunofluorescence: LMTK2 Antibody [NBP1-89320] - Staining of human cell line A-431 shows localization to nuclear speckles & microtubule organizing center.
Immunohistochemistry-Paraffin: LMTK2 Antibody [NBP1-89320]

Immunohistochemistry-Paraffin: LMTK2 Antibody [NBP1-89320]

Immunohistochemistry-Paraffin: LMTK2 Antibody [NBP1-89320] - Staining of human colon shows cytoplasmic positivity in glandular cells.

Applications for LMTK2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LMTK2

The protein encoded by the LMTK2 gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis. (provided by RefSeq)

Long Name

Lemur Tyrosine Kinase 2, Serine/Threonine-protein Kinase LMTK2

Alternate Names

AATK2, BREK, CPRK, KPI-2, LMR2

Gene Symbol

LMTK2

Additional LMTK2 Products

Product Documents for LMTK2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for LMTK2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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