LNK/SH2B3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87867

Novus Biologicals, part of Bio-Techne
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NBP1-87867
NBP1-87867-25ul
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Key Product Details

Species Reactivity

Validated:

Human, Rat

Cited:

Rat

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all LNK/SH2B3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: FDPPKSSRPKLQAACSSIQEVRRCTRLEMPDNLYTFVLKVKDRTDIIFEVGDEQQLNSWMAELSECTGRGLESTEAEMHIPSALEPSTSSSPRGSTDSLNQGASPGGLLDPACQKTDHFLSCYPWFH

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 25172839).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LNK/SH2B3 Antibody

Western Blot: LNK/SH2B3 Antibody [NBP1-87867]

Western Blot: LNK/SH2B3 Antibody [NBP1-87867]

Western Blot: LNK/SH2B3 Antibody [NBP1-87867] - Analysis in human cell line HELA.
Immunocytochemistry/ Immunofluorescence: LNK/SH2B3 Antibody [NBP1-87867]

Immunocytochemistry/ Immunofluorescence: LNK/SH2B3 Antibody [NBP1-87867]

Immunocytochemistry/Immunofluorescence: LNK/SH2B3 Antibody [NBP1-87867] - Staining of human cell line U-2 OS shows localization to nucleoplasm. Antibody staining is shown in green.

Applications for LNK/SH2B3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Western Blot

0.04-0.4 ug/ml
Application Notes
IHC reported in scientific literature (PMID: 25172839). For IHC-Paraffin. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LNK/SH2B3

T-cell activation requires stimulation of the T-cell receptor (TCR; see MIM 186880)-CD3 (see CD3Z; MIM 186780) complex, followed by recruitment of an array of intracellular signaling proteins (e.g., GRB2 (MIM 108355) and PLCG1 (MIM 172420)). Mediating the interaction between the extracellular receptors and intracellular signaling pathways are adaptor proteins such as LAT (MIM 602354), TRIM (MIM 604962), and LNK.[supplied by OMIM]

Long Name

Lymphocyte Adapter Protein

Alternate Names

SH2B3

Gene Symbol

SH2B3

Additional LNK/SH2B3 Products

Product Documents for LNK/SH2B3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for LNK/SH2B3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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