LNK/SH2B3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-06063

Novus Biologicals, part of Bio-Techne
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NBP3-06063-100ul
NBP3-06063-50ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all LNK/SH2B3 Antibodies »

Product Specifications

Immunogen

Produced in rabbits immunized with E. coli-derived Human LNK/SH2B3 fragment.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for LNK/SH2B3 Antibody

Immunocytochemistry/ Immunofluorescence: LNK/SH2B3 Antibody [NBP3-06063]

Immunocytochemistry/ Immunofluorescence: LNK/SH2B3 Antibody [NBP3-06063]

Immunocytochemistry/Immunofluorescence: LNK/SH2B3 Antibody [NBP3-06063] - Immunofluorescence staining of LNK/SH2B3 in U2OS cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-Human SH2B3 polyclonal antibody (dilution ratio 1:200) at 4 degrees celsius overnight. Then cells were stained with the Alexa Fluor (TM) 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Nucleus and Cytoplasm.
Immunohistochemistry-Paraffin: LNK/SH2B3 Antibody [NBP3-06063]

Immunohistochemistry-Paraffin: LNK/SH2B3 Antibody [NBP3-06063]

Immunohistochemistry-Paraffin: LNK/SH2B3 Antibody [NBP3-06063] - Immunochemical staining of human LNK/SH2B3 in human skeletal muscle with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.
Immunohistochemistry: LNK/SH2B3 Antibody [NBP3-06063]

Immunohistochemistry: LNK/SH2B3 Antibody [NBP3-06063]

Immunohistochemistry: LNK/SH2B3 Antibody [NBP3-06063] - Immunochemical staining of human LNK/SH2B3 in human brain with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.

Applications for LNK/SH2B3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:500

Immunohistochemistry-Paraffin

1:200-1:1000

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS

Preservative

0.03% Proclin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LNK/SH2B3

T-cell activation requires stimulation of the T-cell receptor (TCR; see MIM 186880)-CD3 (see CD3Z; MIM 186780) complex, followed by recruitment of an array of intracellular signaling proteins (e.g., GRB2 (MIM 108355) and PLCG1 (MIM 172420)). Mediating the interaction between the extracellular receptors and intracellular signaling pathways are adaptor proteins such as LAT (MIM 602354), TRIM (MIM 604962), and LNK.[supplied by OMIM]

Long Name

Lymphocyte Adapter Protein

Alternate Names

SH2B3

Gene Symbol

SH2B3

Additional LNK/SH2B3 Products

Product Documents for LNK/SH2B3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for LNK/SH2B3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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