LONP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-76504

Novus Biologicals, part of Bio-Techne
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NBP2-76504
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Predicted:

Mouse (97%), Rat (97%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all LONP1 Antibodies »

Product Summary for LONP1 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PAEVLMVEVENVVHEDFQVTEEVKALTAEIVKTIRDIIALNPLYRESVLQMMQAGQRVVDNPIYLSDMGAALTGAESHELQDVLEETNIPKRLYKALSLLKKEFELSKLQQRLGREVEEKIKQTHRKYLLQEQLKIIKKELGLEKDDKDA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LONP1 Antibody

Western Blot: LONP1 Antibody [NBP2-76504]

Western Blot: LONP1 Antibody [NBP2-76504]

Western Blot: LONP1 Antibody [NBP2-76504] - Western blot analysis using Anti-LONP1 antibody NBP2-76504 (A) shows similar pattern to independent antibody NPB1-81734 (B).
Immunocytochemistry/ Immunofluorescence: LONP1 Antibody [NBP2-76504]

Immunocytochemistry/ Immunofluorescence: LONP1 Antibody [NBP2-76504]

Immunocytochemistry/Immunofluorescence: LONP1 Antibody [NBP2-76504] - Staining of human cell line U-251 MG shows localization to nucleus & mitochondria. Antibody staining is shown in green.

Applications for LONP1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Western Blot

0.04-0.4 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, containing 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LONP1

LONP1 encodes a mitochondrial matrix protein in the Lon family of ATP-dependent proteases. A similar E. coli protein regulates gene expression by targeting specific regulatory proteins for degradation. This protein binds a specific sequence in the light and heavy chain promoters of the mitochondrial genome which are involved in regulation of DNA replication and transcription. [provided by RefSeq]

Alternate Names

EC 3.4.21, EC 3.4.21.-, EC 3.4.21.53, hLON, hLON ATP-dependent protease, LON, lon peptidase 1, mitochondrial, lon protease homolog, mitochondrial, Lon protease-like protein, LONHs, LONP, Mitochondrial ATP-dependent protease Lon, mitochondrial lon peptidase 1, mitochondrial lon protease-like protein, PIM1, protease, serine, 15, PRSS15MGC1498, Serine protease 15

Gene Symbol

LONP1

Additional LONP1 Products

Product Documents for LONP1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for LONP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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