Loricrin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-55127

Novus Biologicals, part of Bio-Techne
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NBP1-55127
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

View all Loricrin Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to LOR(loricrin) The peptide sequence was selected from the N terminal of LOR (NP_000418). Peptide sequence GYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSG. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

26 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for Loricrin Antibody

Western Blot: Loricrin Antibody [NBP1-55127]

Western Blot: Loricrin Antibody [NBP1-55127]

Western Blot: Loricrin Antibody [NBP1-55127] - HepG2 cell lysate, Antibody Titration: 5.0ug/ml
Immunohistochemistry-Paraffin: Loricrin Antibody [NBP1-55127]

Immunohistochemistry-Paraffin: Loricrin Antibody [NBP1-55127]

Immunohistochemistry-Paraffin: Loricrin Antibody [NBP1-55127] - Human kidney Tissue, antibody concentration 4-8ug/ml. Cells with positive label: renal corpuscle cells (indicated with arrows) 400X magnification.

Applications for Loricrin Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

4-8 ug/ml

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Loricrin

LOR is a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.LOR encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in LOR may be the cause of both Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.

Alternate Names

loricrin, LRN, MGC111513

Entrez Gene IDs

4014 (Human); 16939 (Mouse)

Gene Symbol

LORICRIN

UniProt

P23490 (Human)

Additional Loricrin Products

Product Documents for Loricrin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Loricrin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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