LOX-1/OLR1 Antibody (001) [DyLight 488]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-89574G

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 001

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all LOX-1/OLR1 Antibodies »

Product Specifications

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Human LOX-1/OLR1 (Uniprot#: P78380; Ser61-Gln273).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Applications for LOX-1/OLR1 Antibody (001) [DyLight 488]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: LOX-1/OLR1

LOX 1 belongs to the C type lectin like protein super family. This unique scavenger receptor plays important roles in atherogenesis. Like other scavenger receptors, LOX 1 has a wide spectrum of physiological ligands, including OxLDL, anionic phospholipids, aged/apoptotic cells, activated platelets, and bacteria. The LOX 1 gene is a so called immediate early gene that is dynamically modulated by several factors in vitro and in vivo. LOX 1 expression is induced by stimuli such as inflammatory cytokines, OxLDL, TNF alpha, TGF beta, and ANG II in vitro, and several proatherogenic factors in vivo.

Long Name

Lectin-like Oxidized Low-density Lipoprotein Receptor 1

Alternate Names

CLEC8A, LOX1, OLR1, SCARE1, SR-E1

Gene Symbol

OLR1

Additional LOX-1/OLR1 Products

Product Documents for LOX-1/OLR1 Antibody (001) [DyLight 488]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for LOX-1/OLR1 Antibody (001) [DyLight 488]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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