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LOXL1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-17158

Novus Biologicals, part of Bio-Techne
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NBP2-17158

Key Product Details

Species Reactivity

Validated:

Human, Zebrafish

Predicted:

Bovine (99%), Mouse (98%), Rat (97%), Xenopus (91%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human LOXL1. The exact sequence is proprietary.

Reactivity Notes

Zebrafish (87%), Xenopus laevis (91%).

Localization

Secreted; extracellular space

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

63 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for LOXL1 Antibody

LOXL1 Antibody

Immunohistochemistry: LOXL1 Antibody [NBP2-17158] -

Immunohistochemistry: LOXL1 Antibody [NBP2-17158] - Immunofluorescent image of a cross-section of a zebrafish embryo using LOXL1 antibody (NBP2-17158) at a 1:200 dilution. LOXL1(Blue) a-Tubulin(Red)(This image was provided courtesy of the Schilling Lab at UC, Irvine.)

Applications for LOXL1 Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: LOXL1

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq]

Long Name

Lysyl Oxidase like 1

Alternate Names

LOXL, Lysyl Oxidase Homolog 1, Lysyl Oxidase like 1

Gene Symbol

LOXL1

UniProt

Additional LOXL1 Products

Product Documents for LOXL1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for LOXL1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.