Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

View all LRP-1 Antibodies »

Product Specifications

Immunogen

Synthetic peptide from the N-terminal of Human Low-density lipoprotein receptor-related protein 1 (aa. 160-260)

Specificity

Detects 80 kDa. Band at 80 kDa is a membrane spanning subunit.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LRP-1 Antibody

Western Blot: LRP-1 Antibody [NBP2-62753]

Western Blot: LRP-1 Antibody [NBP2-62753]

Western Blot: LRP-1 Antibody [NBP2-62753] - Western blot analysis of Mouse, Rat Brain showing detection of 504.6 kDa LRP-1 protein using Rabbit Anti-LRP-1 Polyclonal Antibody (NBP2-62753). Lane 1: Molecular Weight Ladder (MW). Lane 2: Mouse Brain. Lane 3: Rat Brain . Load: 15 ug. Block: 5% Skim Milk powder in TBST. Primary Antibody: Rabbit Anti-LRP-1 Polyclonal Antibody (NBP2-62753) at 1:1000 for 2 hours at RT with shaking. Secondary Antibody: Goat Anti-Rabbit IgG: HRP at 1:5000 for 1 hour at RT. Color Development: ECL solution for 5 min at RT. Predicted/Observed Size: 504.6 kDa. Other Band(s): 80 kDa.
Immunohistochemistry: LRP-1 Antibody [NBP2-62753]

Immunohistochemistry: LRP-1 Antibody [NBP2-62753]

Immunohistochemistry: LRP-1 Antibody [NBP2-62753] - Immunohistochemistry analysis using Rabbit Anti-LRP1 Polyclonal Antibody (NBP2-62753). Tissue: Liver. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-LRP1 Polyclonal Antibody (NBP2-62753) at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X. HRP-DAB Detection.

Applications for LRP-1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50

Western Blot

1:1000
Application Notes
A 1:1000 dilution of was sufficient for detection of LRP-1 in 15 ug of mouse Brain cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS (pH 7.4), 50% Glycerol

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LRP-1

LRP-1 (low-density lipoprotein receptor-related protein 1) is a large type I transmembrane protein belonging to the LDL receptor superfamily. The extracellular domain of LRP-1 is organized in four clusters of ligand-binding repeats that recognizes at least 30 different ligands. The amino acid sequence of human and mouse LRP-1 cluster II share 100% identity.

Long Name

LDL Receptor-related Protein 1

Alternate Names

A2MR, Alpha-2-Macroglobulin Receptor, APOER, Apolipoprotein E receptor, APR, CD91, CD91 antigen, EC 1.1.1.94, EC 3.4.21.9, IGFBP3R, low density lipoprotein receptor-related protein 1, LRP, LRP-1, LRP1A, prolow-density lipoprotein receptor-related protein 1, TbetaR-V/LRP-1/IGFBP-3 receptor, TGFBR5, type V tgf-beta receptor

Gene Symbol

LRP1

Additional LRP-1 Products

Product Documents for LRP-1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for LRP-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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