LST1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24965

Novus Biologicals, part of Bio-Techne
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NBP3-24965
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all LST1 Antibodies »

Product Summary for LST1 Antibody

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein LST1 using the following amino acid sequence: RLPVPSSEGPDLRGRDKRGTKEDPRADYACIAENKP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LST1 Antibody

LST1 Antibody Immunocytochemistry/Immunofluorescence: LST1 Antibody [NBP3-24965]

Immunocytochemistry/Immunofluorescence: LST1 Antibody [NBP3-24965]

Staining of human cell line HEL shows localization to plasma membrane & cytosol.

Applications for LST1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LST1

LST1, also known as Leukocyte-specific transcript 1 protein, has 10 isoforms ranging from a 13 amino acid isoform that is 1 kDa to a 97 amino acid isoform that is 11 kDa, can inhibit the proliferation of lymphocytes, induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may participate in dendritic cell maturation. Disease research is currently being performed with relation to LST1 and vulvovaginitis, rhinotracheitis, chronic venous leg ulcers, proliferative vitreoretinopathy, systemic lupus erythematosus, vitreoretinopathy, rubella, lupus erythematosus, tonsillitis, diabetes mellitus, lung cancer, and Graves' disease. Interactions with this protein have been shown to involve G2E3, PRKCB and CACTIN in cell morphogenesis, immune response, regulation of cell shape, anatomical structure morphogenesis, and dendrite development pathways.

Alternate Names

B144D6S49ELST-1, leucocyte specific transcript 1, leukocyte specific transcript 1, leukocyte-specific transcript 1 protein, lymphocyte antigen 117, MGC119006, MGC119007, Protein B144

Gene Symbol

LST1

Additional LST1 Products

Product Documents for LST1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for LST1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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