Lunatic Fringe Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-39097

Novus Biologicals, part of Bio-Techne
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NBP2-39097
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Rat (92%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Lunatic Fringe/LFNG Antibodies »

Product Summary for Lunatic Fringe Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: TKKFHRARLDLLLETWISRHKEMTFIFTDGEDEALARHTGNVVITNCSAAH

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (88%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Lunatic Fringe Antibody

Western Blot: Lunatic Fringe Antibody [NBP2-39097]

Western Blot: Lunatic Fringe Antibody [NBP2-39097]

Western Blot: Lunatic Fringe Antibody [NBP2-39097] - Analysis in human plasma.
Immunohistochemistry-Paraffin: Lunatic Fringe Antibody [NBP2-39097]

Immunohistochemistry-Paraffin: Lunatic Fringe Antibody [NBP2-39097]

Immunohistochemistry-Paraffin: Lunatic Fringe Antibody [NBP2-39097] - Staining of human liver shows very weak granular cytoplasmic positivity in hepatocytes.
Immunohistochemistry-Paraffin: Lunatic Fringe Antibody [NBP2-39097]

Immunohistochemistry-Paraffin: Lunatic Fringe Antibody [NBP2-39097]

Immunohistochemistry-Paraffin: Lunatic Fringe Antibody [NBP2-39097] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules.
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Applications for Lunatic Fringe Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Lunatic Fringe/LFNG

Lunatic Fringe encodes a member of the glycosyltransferase superfamily. The encoded protein is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransferase, adding an N-acetylglucosamine to the fucose residue of a group of signaling receptors involved in regulating cell fate decisions during development. Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Alternatively spliced transcript variants that encode different isoforms have been described, however, not all variants have been fully characterized.

Long Name

LFNG O-Fucosylpeptide 3-Beta-N-Acetylglucosaminyltransferase

Alternate Names

EC 2.4.1.222, LFNG, SCDO3

Gene Symbol

LFNG

UniProt

Q8NES3 (Human)

Additional Lunatic Fringe/LFNG Products

Product Documents for Lunatic Fringe Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Lunatic Fringe Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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