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Ly-49l Antibody (YLI-90) [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-28094

Novus Biologicals, part of Bio-Techne
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NBP1-28094

Key Product Details

Species Reactivity

Mouse

Applications

Flow Cytometry

Label

Biotin

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # YLI-90

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

CHO-K1 cells transfected with B6 allele of Ly49I gene

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Specificity

B6 allele of the Ly49I receptor

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Applications for Ly-49l Antibody (YLI-90) [Biotin]

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Ly-49l

The monoclonal antibody YLI-90 reacts with the B6 allele of Ly49I, a member of the lectin-like homodimeric Ly49 family of cell surface receptors. (1) Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down-regulated. (2) These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells. The YLI-90 antibody stains approx. 45% of NK1.1+CD3- splenocytes from C57BL/6 mice. (1)

Alternate Names

Killer cell lectin like receptor subfamily A member 9, Klra9, Ly49I receptor, LY49I1

Additional Ly-49l Products

Product Documents for Ly-49l Antibody (YLI-90) [Biotin]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Ly-49l Antibody (YLI-90) [Biotin]

Protect conjugated forms from light.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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