LYK5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89577

Novus Biologicals, part of Bio-Techne
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NBP1-89577
NBP1-89577-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (92%), Rat (91%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all LYK5 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: MLLEKLNGTVPCLLDTSTIPAEELTMSPSRSVANSGLSDSLTTSTPRPSNGDSPSHPYHRTFSPHFHHFVEQCLQRNPDARPSASTLLNHSFFKQIKRRASEALPELLRPVTPITNFEGSQSQDHSG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LYK5 Antibody

Immunocytochemistry/ Immunofluorescence: LYK5 Antibody [NBP1-89577]

Immunocytochemistry/ Immunofluorescence: LYK5 Antibody [NBP1-89577]

Immunocytochemistry/Immunofluorescence: LYK5 Antibody [NBP1-89577] - Immunofluorescent staining of human cell line A549 shows localization to nucleoplasm & cytosol.
Immunohistochemistry-Paraffin: LYK5 Antibody [NBP1-89577]

Immunohistochemistry-Paraffin: LYK5 Antibody [NBP1-89577]

Immunohistochemistry-Paraffin: LYK5 Antibody [NBP1-89577] - Staining of human duodenum shows strong cytoplasmic and nuclear positivity in glandular cells.
Immunohistochemistry: LYK5 Antibody [NBP1-89577]

Immunohistochemistry: LYK5 Antibody [NBP1-89577]

Immunohistochemistry: LYK5 Antibody [NBP1-89577] - Staining of human duodenum shows strong cytoplasmic and nuclear positivity in glandular cells.

Applications for LYK5 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LYK5

The protein encoded by the LYK5 gene contains a STE20-like kinase domain, but lacks several residues that are critical forcatalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex withserine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39,also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has beenshown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcriptvariants encoding different isoforms have been found for this gene. Additional transcript variants have been describedbut their full-length nature is not known. (provided by RefSeq)

Alternate Names

LYK5FLJ90524, NY-BR-96, protein kinase LYK5, Serologically defined breast cancer antigen NY-BR-96, STE20-like pseudokinase, STE20-related adapter protein, STE20-related adaptor protein, STE20-related kinase adapter protein alpha, STE20-related kinase adaptor alpha, Stlk, STRAD alpha, STRADPMSE

Gene Symbol

STRADA

Additional LYK5 Products

Product Documents for LYK5 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for LYK5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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