Lyp/PTPN22 Antibody (1A6)

Novus Biologicals, part of Bio-Techne | Catalog # H00026191-M02

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 1A6

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Lyp Antibodies »

Product Specifications

Immunogen

PTPN22 (NP_057051.2, 10 a.a. ~ 113 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. FLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRYKDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDF

Specificity

Reacts with protein tyrosine phosphatase, non-receptor type 22 (lymphoid).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for Lyp/PTPN22 Antibody (1A6)

Immunocytochemistry/ Immunofluorescence: Lyp/PTPN22 Antibody (1A6) [H00026191-M02]

Immunocytochemistry/ Immunofluorescence: Lyp/PTPN22 Antibody (1A6) [H00026191-M02]

Immunocytochemistry/Immunofluorescence: Lyp/PTPN22 Antibody (1A6) [H00026191-M02] - Analysis of monoclonal antibody to PTPN22 on HeLa cell . Antibody concentration 10 ug/ml.

Applications for Lyp/PTPN22 Antibody (1A6)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody is reactive against recombinant protein in western blot and ELISA.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Lyp

This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]

Long Name

Lymphoid Phosphatase

Alternate Names

LyPTP, PEP, PTPN22, PTPN8 (former)

Entrez Gene IDs

26191 (Human)

Gene Symbol

PTPN22

UniProt

NP_057051 (Human)

Additional Lyp Products

Product Documents for Lyp/PTPN22 Antibody (1A6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Lyp/PTPN22 Antibody (1A6)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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