Lysosomal Pro-X Carboxypeptidase/PRCP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00005547-D01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Lysosomal Pro-X Carboxypeptidase/PRCP Antibodies »

Product Specifications

Immunogen

PRCP (NP_005031.1, 1 a.a. - 496 a.a.) full-length human protein. MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKVDHFGFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQH

Specificity

Reacts with prolylcarboxypeptidase (angiotensinase C).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for Lysosomal Pro-X Carboxypeptidase/PRCP Antibody

Western Blot: Lysosomal Pro-X Carboxypeptidase/PRCP Antibody [H00005547-D01P]

Western Blot: Lysosomal Pro-X Carboxypeptidase/PRCP Antibody [H00005547-D01P]

Western Blot: Lysosomal Pro-X Carboxypeptidase/PRCP Antibody [H00005547-D01P] - Analysis of PRCP expression in transfected 293T cell line by PRCP polyclonal antibody.Lane 1: PRCP transfected lysate(55.80 KDa).Lane 2: Non-transfected lysate.

Applications for Lysosomal Pro-X Carboxypeptidase/PRCP Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody is reactive against transfected lysate in WB and as a detection antibody in ELISA.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Lysosomal Pro-X Carboxypeptidase/PRCP

The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]

Alternate Names

Angiotensinase C, HUMPCP, Prolylcarboxypeptidase

Entrez Gene IDs

5547 (Human)

Gene Symbol

PRCP

UniProt

NP_005031.1 (Human)

Additional Lysosomal Pro-X Carboxypeptidase/PRCP Products

Product Documents for Lysosomal Pro-X Carboxypeptidase/PRCP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Lysosomal Pro-X Carboxypeptidase/PRCP Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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