Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%), Rabbit (94%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all LZTR2 Antibodies »

Product Specifications

Immunogen

Antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human LZTR2. The immunogen is located within the last 50 amino acids of LZTR2. Amino Acid Squence: TSLNRPNRLAQRRYPTQP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LZTR2 Antibody - BSA Free

Western Blot: LZTR2 AntibodyBSA Free [NBP1-77122]

Western Blot: LZTR2 AntibodyBSA Free [NBP1-77122]

Western Blot: LZTR2 Antibody [NBP1-77122] - WB Validation in 293 Cells. Loading: 10 ug of cell lysate. Antibodies: LZTR2 5623-1001, 0.5 ug/mL, 1 h incubation at RT in 5% NFDM/TBST. Secondary: Goat Anti-Rabbit IgG HRP conjugate at 1:10000 dilution. Exposure: 10 sec. Lane 1: In the absence of peptide blocking. Lane 2: In the presence of peptide blocking.
Immunocytochemistry/ Immunofluorescence: LZTR2 Antibody - BSA Free [NBP1-77122]

Immunocytochemistry/ Immunofluorescence: LZTR2 Antibody - BSA Free [NBP1-77122]

Immunocytochemistry/Immunofluorescence: LZTR2 Antibody [NBP1-77122] - Mouse kidney tissue
Immunohistochemistry-Paraffin: LZTR2 Antibody - BSA Free [NBP1-77122]

Immunohistochemistry-Paraffin: LZTR2 Antibody - BSA Free [NBP1-77122]

Immunohistochemistry-Paraffin: LZTR2 Antibody [NBP1-77122] - Mouse kidney tissue with LZTR2 antibody at 5 ug/mL.
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Applications for LZTR2 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100 - 1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Immunohistochemistry

5 ug/mL

Immunohistochemistry-Paraffin

5 ug/mL

Western Blot

1 ug/mL

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LZTR2

LZTR2, also known as RGPR-p117, is a member of the BTB-kelch superfamily and was initially described as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene. LZTR2 is cytoplasmically localized but is thought to translocate to the nucleus, a process mediated by protein kinase C signaling following hormonal stimulation. Recent evidence has suggested that there is a strong correlation of single nucleotide polymorphisms of LZTR2 with obesity in the Japanese population similar to that seen with the TMEM18 gene and the GNPDA2, BDNF, FAIM2, and MC4R genes with obesity in Caucasian populations, suggesting LZTR2 may play a role in metabolism and obesity risk.

Alternate Names

DKFZp686C2486, FLJ23871, FLJ25761, KIAA1928, Leucine zipper transcription regulator 2FLJ36620, LZTR2SEC16Sprotein SEC16 homolog B, PGPR-p117, protein transport protein Sec16B, Regucalcin gene promoter region-related protein p117, regucalcin gene promotor region related protein, RGPRFLJ33652, RGPR-p117, SEC16 homolog B, SEC16 homolog B (S. cerevisiae)

Gene Symbol

SEC16B

UniProt

NP_149118 (Human)

Additional LZTR2 Products

Product Documents for LZTR2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for LZTR2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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