M-CSFR/CD115 Antibody (S06-5H8)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19684

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S06-5H8

Concentration

0.3 mg/ml

View all M-CSF R/CD115 Antibodies »

Product Specifications

Immunogen

Recombinant protein of mouse M-CSFR/CD115 (Uniprot # P09581)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

109 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for M-CSFR/CD115 Antibody (S06-5H8)

Western Blot: M-CSFR/CD115 Antibody (S06-5H8) [NBP3-19684]

Western Blot: M-CSFR/CD115 Antibody (S06-5H8) [NBP3-19684]

Western Blot: M-CSFR/CD115 Antibody (S06-5H8) [NBP3-19684] - Western blot detection of M-CSFR/CD115 in K562 cell lysates using NBP3-19684 (1:1000 diluted). Predicted band size: 109kDa. Observed band size: 109kDa.

Applications for M-CSFR/CD115 Antibody (S06-5H8)

Application
Recommended Usage

Western Blot

1/1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: M-CSF R/CD115

MCSF Receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.

Long Name

Macrophage Colony Stimulating Factor Receptor

Alternate Names

c-fms, CD115, CSF1R, M-CSFR, MCSFR

Gene Symbol

CSF1R

Additional M-CSF R/CD115 Products

Product Documents for M-CSFR/CD115 Antibody (S06-5H8)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for M-CSFR/CD115 Antibody (S06-5H8)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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