Macrophage Antibody (MOMA-2)

Novus Biologicals, part of Bio-Techne | Catalog # NB100-64946

Novus Biologicals, part of Bio-Techne
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NB100-64946
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Key Product Details

Validated by

Knockout/Knockdown

Species Reactivity

Validated:

Mouse

Cited:

Mouse

Applications

Validated:

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Knockout Validated

Cited:

Immunohistochemistry

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2B Clone # MOMA-2

Concentration

0.5 mg/ml

View all Macrophage Antibodies »

Product Specifications

Immunogen

Mouse lymph node stroma

Specificity

Recognizes an intracellular antigen of mouse macrophages and monocytes. It reacts strongly with macrophages in lymphoid organs in all mouse strains tested. Staining may also be seen on the epithelium of mucosa.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2B

Scientific Data Images for Macrophage Antibody (MOMA-2)

Immunocytochemistry/ Immunofluorescence: Macrophage Antibody (MOMA-2) - BSA Free [NB100-64946]

Immunocytochemistry/ Immunofluorescence: Macrophage Antibody (MOMA-2) - BSA Free [NB100-64946]

Immunocytochemistry/Immunofluorescence: Macrophage Antibody (MOMA-2) [NB100-64946] - Cabanel M, Brand C, Oliveira-Nunes MC, Cabral-Piccin MP, Lopes MF, Brito JM, et al. (2015) Epigenetic Control of Macrophage Shape Transition towards an Atypical Elongated Phenotype by Histone Deacetylase Activity. PLoS ONE 10(7): e0132984.
Immunohistochemistry: Macrophage Antibody (MOMA-2) - BSA Free [NB100-64946]

Immunohistochemistry: Macrophage Antibody (MOMA-2) - BSA Free [NB100-64946]

Immunohistochemistry: Macrophage Antibody (MOMA-2) [NB100-64946] - Benard A, Sala C, Pluschke G (2016)Mycobacterium ulcerans Mouse Model Refinement for Pre-Clinical Profiling of Vaccine Candidates.PLoS ONE 11(11): e0167059
Flow Cytometry: Macrophage Antibody (MOMA-2) - BSA Free [NB100-64946]

Flow Cytometry: Macrophage Antibody (MOMA-2) - BSA Free [NB100-64946]

Flow Cytometry: Macrophage Antibody (MOMA-2) [NB100-64946] - Staining of mouse peritoneal macrophages with RPE conjugated Rat anti Mouse Macrophages/Monocytes following permeabilisation with Leucoperm
View 16 more images

Applications for Macrophage Antibody (MOMA-2)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Frozen

Optimal dilutions of this antibody should be experimentally determined.

Knockout Validated

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

<0.1% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Macrophage

Macrophages comprise of many forms of mononuclear phagocytes found in tissues. Mononuclear phagocytes arise from hematopoietic stem cells in the bone marrow. After passing through the monoblast and promonocyte states of the monocyte stage, they enter the blood, where they circulate for about 40 hours. They then enter tissues and increase in size, phagocytic activity, and lysosomal enzyme content becoming macrophages. Among the functions of macrophages are nonspecific phagocytosis and pinocytosis, specific phagocytosis of opsonized microorganisms mediated by Fc receptors and complement receptors, killing of ingested microorganisms, digestion and presentation of antigens to T and B lymphocytes, and secretion of a large number of diverse products, including many enzymes including lysozyme and collagenases, several complement components and coagulation factors, some prostaglandins and leukotrienes, and many regulatory molecules (Interferon, Interleukin 1). Among cells that are now recognized as macrophages are histiocytes, Kupffer cells, osteoclasts, microglial cells, synovial type A cells, interdigitating cells, and Langerhans cells (in normal tissues) and epithelioid cells and Langerhans-type and foreign-body-type multinucleated giant cells (in inflamed tissues).

Alternate Names

EC 5.3.2.1, EC 5.3.3.12, GIFmacrophage migration inhibitory factor, GLIF, Glycosylation-inhibiting factor, L-dopachrome isomerase, L-dopachrome tautomerase, macrophage migration inhibitory factor (glycosylation-inhibiting factor), MMIF, Phenylpyruvate tautomerase

Additional Macrophage Products

Product Documents for Macrophage Antibody (MOMA-2)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Macrophage Antibody (MOMA-2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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