MADD Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85258

Novus Biologicals, part of Bio-Techne
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NBP1-85258
NBP1-85258-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (98%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MADD Antibodies »

Product Summary for MADD Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: YSQQINEVLDQLANLNGRDLSIWSSGSRHMKKQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRRNGSETQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MADD Antibody

Immunocytochemistry/ Immunofluorescence: MADD Antibody [NBP1-85258]

Immunocytochemistry/ Immunofluorescence: MADD Antibody [NBP1-85258]

Immunocytochemistry/Immunofluorescence: MADD Antibody [NBP1-85258] - Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.
Immunohistochemistry-Paraffin: MADD Antibody [NBP1-85258]

Immunohistochemistry-Paraffin: MADD Antibody [NBP1-85258]

Immunohistochemistry-Paraffin: MADD Antibody [NBP1-85258] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in neuropil.

Applications for MADD Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MADD

MAP kinase-activating death domain protein (MADD) is a death domain containing protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activate protein kinase (MAPK) and transduce apoptotic signals. MADD is a multi-pass membrane protein that exists as multiple alternatively spliced forms.

Alternate Names

DENNFLJ36300, Differentially expressed in normal and neoplastic cells, FLJ35600, IG20, Insulinoma glucagonoma clone 20, insulinoma-glucagonoma protein 20, KIAA0358RAB3GEP, MAP kinase-activating death domain protein, MAP-kinase activating death domain, Rab3 GDP/GTP exchange factor

Gene Symbol

MADD

Additional MADD Products

Product Documents for MADD Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MADD Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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