MAGEA4 Antibody (CPTC-MAGEA4-1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-79726

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2c Kappa Clone # CPTC-MAGEA4-1

Concentration

0.2 mg/ml

View all MAGEA4 Antibodies »

Product Summary for MAGEA4 Antibody (CPTC-MAGEA4-1)

Immunogen

Recombinant full-length human MAGEA4 protein (Uniprot: P43358)

Localization

Cytoplasmic, Nuclear

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2c Kappa

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP2-79861)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for MAGEA4 Antibody (CPTC-MAGEA4-1)

Immunohistochemistry-Paraffin: MAGEA4 Antibody (CPTC-MAGEA4-1) [NBP2-79726]

Immunohistochemistry-Paraffin: MAGEA4 Antibody (CPTC-MAGEA4-1) [NBP2-79726]

Immunohistochemistry-Paraffin: MAGEA4 Antibody (CPTC-MAGEA4-1) [NBP2-79726] - Formalin-fixed, paraffin-embedded human Testis stained with MAGEA4 Antibody (CPTC-MAGEA4-1).
Protein Array: MAGEA4 Antibody (CPTC-MAGEA4-1) [NBP2-79726]

Protein Array: MAGEA4 Antibody (CPTC-MAGEA4-1) [NBP2-79726]

Protein Array: MAGEA4 Antibody (CPTC-MAGEA4-1) [NBP2-79726] - Analysis of Protein Array containing more than 19,000 full-length human proteins using MAGEA4 Antibody (CPTC-MAGEA4-1). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target, if the Monoclonal Antibody has an S-score of at least 2.5

Applications for MAGEA4 Antibody (CPTC-MAGEA4-1)

Application
Recommended Usage

Immunohistochemistry

1-2 ug/ml

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: MAGEA4

MAGEA4 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene.

Long Name

Melanoma-Associated Antigen 4

Alternate Names

CT1.4, MAGE-41, MAGE-X2, MAGE4A, MAGE4B

Gene Symbol

MAGEA4

UniProt

P43358 (Human)

Additional MAGEA4 Products

Product Documents for MAGEA4 Antibody (CPTC-MAGEA4-1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MAGEA4 Antibody (CPTC-MAGEA4-1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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