MALT1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-24732

Novus Biologicals, part of Bio-Techne
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NBP2-24732
NBP2-24732SS
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all MALT1 Antibodies »

Product Specifications

Immunogen

A synthetic peptide corresponding to amino acids 43-57 ELLDQAPEGRGWRRL of human MALT1 (GenBank No. NP_776216.1) was used as immunogen. The immunogen sequence is 100% conserved between Malt1 isoforms a and b.

Specificity

The antibody was tested on a cell line transfected with full-length SARS Nucleocapsid cDNA with a predicted molecular weight 46 kDa.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MALT1 Antibody

Western Blot: MALT1 Antibody [NBP2-24732]

Western Blot: MALT1 Antibody [NBP2-24732]

Western Blot: MALT1 Antibody [NBP2-24732] - Western bot analysis of MALT1 in Jurkat cell lysate using NBP2-24732 at 0.5 ug/ml.

Applications for MALT1 Antibody

Application
Recommended Usage

Western Blot

0.5-2 ug/ml

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

0.2 ml PBS and 0.2% Gelatin

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MALT1

Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1), also known as MLT1 or paracaspase 1, is a member of the human paracaspase family and an interacting partner of B-cell lymphoma 10 (Bcl-10) (1). In vitro, In vitro, MALT1 synergizes with BCL10 to enhance nuclear factor B activation (2) and to mediate IB kinase (IKK) activation by facilitating the ubiquitinylation of the NF-B essential modulator (NEMO) (3). MALT1 is found in recurrent chromosomal translocations in non-Hodgkin B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT). One common translocation juxtaposes the MALT1 gene to the IgH promoter region, resulting in up-regulation of Bcl-10 and MALT1 (4). Another common translocation creates a fusion between MALT1 and the inhibitor of apoptosis gene API2 (cIAP2/HIAP1) (5).

Long Name

Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1

Alternate Names

MLT1, Paracaspase

Gene Symbol

MALT1

UniProt

Q9UDY8 (Human)

Additional MALT1 Products

Product Documents for MALT1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for MALT1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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