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MAML1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-33638

Novus Biologicals, part of Bio-Techne
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NBP1-33638

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for MAML1 Antibody

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human MAML1. The exact sequence is proprietary.

Localization

Nucleus speckle

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

108 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for MAML1 Antibody

Western Blot: MAML1 Antibody [NBP1-33638]

Western Blot: MAML1 Antibody [NBP1-33638]

Western Blot: MAML1 Antibody [NBP1-33638] - Sample (30 ug of whole cell lysate) A: HeLa B: HeLa nucleus 7.5% SDS PAGE; antibody diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: MAML1 Antibody [NBP1-33638]

Immunocytochemistry/ Immunofluorescence: MAML1 Antibody [NBP1-33638]

Immunocytochemistry/Immunofluorescence: MAML1 Antibody [NBP1-33638] - Paraformaldehyde-fixed HeLa, using MAML1 antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with an alpha Tubulin antibody (Red) at 1:2500.
Western Blot: MAML1 Antibody [NBP1-33638]

Western Blot: MAML1 Antibody [NBP1-33638]

Western Blot: MAML1 Antibody [NBP1-33638] - Sample (50 ug of whole cell lysate) A: mouse heart 7. 5% SDS PAGE; antibody diluted at 1:1000.

Applications for MAML1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: MAML1

This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.

Alternate Names

FLJ53540, KIAA0200Mam1, Mam-1mastermind homolog, mastermind (drosophila)-like 1, mastermind-like 1 (Drosophila), mastermind-like protein 1

Gene Symbol

MAML1

Additional MAML1 Products

Product Documents for MAML1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MAML1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.