MANF Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-06020

Novus Biologicals, part of Bio-Techne
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NBP1-06020
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Canine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all MANF Antibodies »

Product Summary for MANF Antibody

Immunogen

Peptide with sequence KFCREARGKENR corresponding to internal region according to NP_006001.2.

Epitope

KFCREARGKENR

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for MANF Antibody

Western Blot: MANF Antibody [NBP1-06020]

Western Blot: MANF Antibody [NBP1-06020]

Western Blot: ARMET Antibody [NBP1-06020] - Analysis of ARMET using this antibody at 0.3 ug/ml in Human Pancreas lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for MANF Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:16000

Western Blot

0.3 - 1 ug/ml
Application Notes
WB: Approx. 21 kDa band observed in human pancreas lysates (calculated MW of 21.1 kDa band according to NP_006001.2).
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: MANF

The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of a specific mutation changing the previously numbered codon 50 from ATG to AGG, or deletion of that codon, has been reported in a variety of solid tumors. With the protein size correction, this codon is now identified as the initiation codon. [provided by RefSeq]

Long Name

Mesencephalic Astrocyte-derived Neurotrphic Factor

Alternate Names

ARMET, ARP

Entrez Gene IDs

7873 (Human); 74840 (Mouse); 315989 (Rat)

Gene Symbol

MANF

UniProt

NP_006001.2 (Human)

Additional MANF Products

Product Documents for MANF Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for MANF Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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