MAP3K6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-14219

Novus Biologicals, part of Bio-Techne
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NBP2-14219
NBP2-14219-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MAP3K6 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: EEPASPEESSGLSLLHQESKRRAMLAAVLEQELPALAENLHQEQKQEQGARLGRNHVEELLRCLGAHIHTPNRR

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (81%), Rat (84%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MAP3K6 Antibody

Immunocytochemistry/ Immunofluorescence: MAP3K6 Antibody [NBP2-14219]

Immunocytochemistry/ Immunofluorescence: MAP3K6 Antibody [NBP2-14219]

Immunocytochemistry/Immunofluorescence: MAP3K6 Antibody [NBP2-14219] - Immunofluorescent staining of human cell line MCF7 shows localization to nucleus & cytosol.
Immunohistochemistry-Paraffin: MAP3K6 Antibody [NBP2-14219]

Immunohistochemistry-Paraffin: MAP3K6 Antibody [NBP2-14219]

Immunohistochemistry-Paraffin: MAP3K6 Antibody [NBP2-14219] - Staining of human smooth muscle shows strong cytoplasmic positivity in smooth muscle cells.

Applications for MAP3K6 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MAP3K6

MAP3K6 encodes a member of the serine/threonine protein kinase family. The encoded kinase was identified by its interaction with MAP3K5/ASK, a protein kinase and an activator of c-Jun kinase (MAPK7/JNK) and MAPK14/p38 kinase. This kinase was found to weakly activate MAPK7, but not MAPK1/ERK or MAPK14. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined.

Alternate Names

apoptosis signal regulating kinase 2, ASK2MGC20114, EC 2.7.11, EC 2.7.11.25, MAPKKK6MEKK6Apoptosis signal-regulating kinase 2, MGC125653, mitogen-activated protein kinase kinase kinase 6

Gene Symbol

MAP3K6

Additional MAP3K6 Products

Product Documents for MAP3K6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MAP3K6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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