MAP4K6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-22988

Novus Biologicals, part of Bio-Techne
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NBP1-22988
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Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Validated:

Human, Mouse

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all MAP4K6 Antibodies »

Product Summary for MAP4K6 Antibody

Immunogen

The immunogen recognized by this antibody maps to a region between residue 1 and 50 of human misshapen-like kinase 1 using the numbering given in entry NP_722549.2 (GeneID 50488).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MAP4K6 Antibody

Western Blot: MAP4K6 Antibody [NBP1-22988]

Western Blot: MAP4K6 Antibody [NBP1-22988]

Western Blot: MAP4K6 Antibody [NBP1-22988] - Whole cell lysate from HeLa and mouse NIH3T3 cells. NBP1-22988 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate.

Applications for MAP4K6 Antibody

Application
Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000
Application Notes
Western blot of lysates performed using standard western blot reagents and 4-8% SDS-PAGE.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: MAP4K6

MINK1 (misshapen/NIKs-related kinase 1) is a member of the germinal center kinase (GCK) family that are homologous to the yeast sterile 20 (Ste20) kinases. GCKs function in the activation of the JNK pathway. MINK1 has been found to activate the JNK pathway and may have a role in modulating cytoskeletal organization, cell adhesion, and cell migration during development.

Alternate Names

B55, EC 2.7.11, GCK family kinase MiNK, hMINK, hMINKbeta, MAP4K6EC 2.7.11.1, MAPK/ERK kinase kinase kinase 6, MEK kinase kinase 6, MGC21111, MINKMEKKK 6, Misshapen/NIK-related kinase, misshapen-like kinase 1, misshapen-like kinase 1 (zebrafish), Mitogen-activated protein kinase kinase kinase kinase 6, serine/threonine protein kinase, YSK2, ZC3

Entrez Gene IDs

50488 (Human)

Gene Symbol

MINK1

UniProt

NP_722549.2 (Human)

Additional MAP4K6 Products

Product Documents for MAP4K6 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for MAP4K6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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