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MASTL Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83680

Novus Biologicals, part of Bio-Techne
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NBP1-83680
NBP1-83680-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: TSQLGFHQSNQWAVDSGGISEEHLGKRSLKRNFELVDSSPCKKIIQNKKTCVEYKHNEMTNCYTNQNTGLTVEVQDLKLSVHKSQQNDCANKEN

Reactivity Notes

Reactivity reported in scientific literature (PMID: 24391510)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MASTL Antibody

Western Blot: MASTL Antibody [NBP1-83680]

Western Blot: MASTL Antibody [NBP1-83680]

Western Blot: MASTL Antibody [NBP1-83680] - Analysis in control (vector only transfected HEK293T lysate) and mASTL over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunocytochemistry/ Immunofluorescence: MASTL Antibody [NBP1-83680]

Immunocytochemistry/ Immunofluorescence: MASTL Antibody [NBP1-83680]

Immunocytochemistry/Immunofluorescence: MASTL Antibody [NBP1-83680] - Staining of human cell line A-431 shows localization to nucleoplasm. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: MASTL Antibody [NBP1-83680]

Immunohistochemistry-Paraffin: MASTL Antibody [NBP1-83680]

Immunohistochemistry-Paraffin: MASTL Antibody [NBP1-83680] - Staining of human rectum shows strong cytoplasmic positivity in lymphoid cells.

Applications for MASTL Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MASTL

MASTL (microtubule-associated serine/threonine-protein kinase-like) is an uncharacterized putative serine/threonine kinase which may be involved in megakaryocyte development. Defects in MASTL are the cause of thrombocytopenia type 2 (THC2) a disease characterized by decreased circulating platelets and increased potential for bleeding.

Long Name

MASTL

Alternate Names

Greatwall, THC2

Gene Symbol

MASTL

Additional MASTL Products

Product Documents for MASTL Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MASTL Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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