MAT1A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-33533

Novus Biologicals, part of Bio-Techne
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NBP2-33533
NBP2-33533-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (92%), Rat (92%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MAT1A Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: MNGPVDGLCDHSLSEGVFMFTSESV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MAT1A Antibody

Immunohistochemistry-Paraffin: MAT1A Antibody [NBP2-33533]

Immunohistochemistry-Paraffin: MAT1A Antibody [NBP2-33533]

Immunohistochemistry-Paraffin: MAT1A Antibody [NBP2-33533] - Staining of human liver shows strong cytoplasmic and nuclear positivity in hepatocytes.

Staining of human fallopian tube shows no positivity in glandular cells as expected.

Staining of human fallopian tube shows no positivity in glandular cells as expected.

Staining of human skeletal muscle shows no positivity in myocytes as expected.

Staining of human skeletal muscle shows no positivity in myocytes as expected.
View 1 more images

Applications for MAT1A Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MAT1A

MAT1A and MAT2A are catalytic subunits of methionine adenosyltransferase (MAT), which catalyzes the formation of S-adenosyltransferase for methionine catabolism. Inactivation of MAT1A has been linked to liver disease. In addition, in certain liver cancers, expression of MAT1A is replaced by expression of MAT1B. Overexpression of MAT2A has also been observed in colon cancer, leading to the proposal that MAT2A facilitates cancer cell growth.

MAT1A and MAT2A antibodies are useful tools for cancer research and liver function research.

Alternate Names

AdoMet synthase 1, adoMet synthetase 1, AMS1, MAT, MATA1MAT 1, MAT-I/III, Methionine adenosyltransferase 1, methionine adenosyltransferase I, alpha, Methionine adenosyltransferase I/III, S-adenosylmethionine synthase isoform type-1, S-adenosylmethionine synthetase isoform type-1, SAMS, SAMS1EC 2.5.1.6

Gene Symbol

MAT1A

UniProt

Q00266 (Human)

Additional MAT1A Products

Product Documents for MAT1A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for MAT1A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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