MAVS Antibody (Adri-1) [PE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-80052PE

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP2-80052AF350

Alexa Fluor 405

NBP2-80052AF405

Alexa Fluor 488

NBP2-80052AF488

Alexa Fluor 532

NBP2-80052AF532

Alexa Fluor 594

NBP2-80052AF594

Alexa Fluor 647

NBP2-80052AF647

Alexa Fluor 700

NBP2-80052AF700

Alexa Fluor 750

NBP2-80052AF750

Allophycocyanin

NBP2-80052APC

Biotin

NBP2-80052B

CoraFluor 1

NBP2-80052CL1

DyLight 350

NBP2-80052UV

DyLight 405

NBP2-80052V

DyLight 488

NBP2-80052G

DyLight 550

NBP2-80052R

DyLight 594

NBP2-80052DL594

DyLight 650

NBP2-80052C

DyLight 680

NBP2-80052FR

DyLight 755

NBP2-80052IR

FITC

NBP2-80052F

HRP

NBP2-80052H

Janelia Fluor 525

NBP2-80052JF525

Janelia Fluor 549

NBP2-80052JF549

Janelia Fluor 585

NBP2-80052JF585

Janelia Fluor 635

NBP2-80052JF635

Janelia Fluor 646

NBP2-80052JF646

Janelia Fluor 669

NBP2-80052JF669

PerCP

NBP2-80052PCP

Forumulation

Catalog #

BSA Free

NBP2-80052

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Monoclonal Mouse IgG_2B Clone # Adri-1

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MAVS Antibodies »

Product Summary for MAVS Antibody (Adri-1) [PE]

Immunogen

Recombinant human MAVS (aa 160-450).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2B

Applications for MAVS Antibody (Adri-1) [PE]

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: MAVS

Double-stranded RNA viruses are recognized in a cell type-dependent manner by the transmembrane receptor TLR3 (MIM 603029) or by the cytoplasmic RNA helicases MDA5 (MIM 606951) and RIGI (ROBO3; MIM 608630). These interactions initiate signaling pathways that differ in their initial steps but converge in the activation of the protein kinases IKKA (CHUK; MIM 600664) and IKKB (IKBKB; MIM 603258), which activate NFKB (see MIM 164011), or TBK1 (MIM 604834) and IKKE (IKBKE; MIM 605048), which activate IRF3 (MIM 603734). Activated IRF3 and NFKB induce transcription of IFNB (IFNB1; MIM 147640). For the TLR3 pathway, the intermediary molecule before the pathways converge is the cytoplasmic protein TRIF (TICAM1; MIM 607601). For RIGI, the intermediary protein is mitochondria-bound IPS1 (Sen and Sarkar, 2005).[supplied by OMIM]

Long Name

Mitochondrial Antiviral Signaling Protein

Alternate Names

Cardif, IPS-1, VISA

Gene Symbol

MAVS

Additional MAVS Products

Product Documents for MAVS Antibody (Adri-1) [PE]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for MAVS Antibody (Adri-1) [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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