MAVS Antibody [DyLight 488]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76768G

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP1-76768AF350

Alexa Fluor 405

NBP1-76768AF405

Alexa Fluor 488

NBP1-76768AF488

Alexa Fluor 532

NBP1-76768AF532

Alexa Fluor 594

NBP1-76768AF594

Alexa Fluor 647

NBP1-76768AF647

Alexa Fluor 700

NBP1-76768AF700

Alexa Fluor 750

NBP1-76768AF750

Biotin

NBP1-76768B

CoraFluor 1

NBP1-76768CL1

DyLight 350

NBP1-76768UV

DyLight 405

NBP1-76768V

DyLight 550

NBP1-76768R

DyLight 594

NBP1-76768DL594

DyLight 650

NBP1-76768C

DyLight 680

NBP1-76768FR

DyLight 755

NBP1-76768IR

FITC

NBP1-76768F

HRP

NBP1-76768H

Janelia Fluor 525

NBP1-76768JF525

Janelia Fluor 549

NBP1-76768JF549

Janelia Fluor 585

NBP1-76768JF585

Janelia Fluor 635

NBP1-76768JF635

Janelia Fluor 646

NBP1-76768JF646

Janelia Fluor 669

NBP1-76768JF669

mFluor Violet 450 SE

NBP1-76768MFV450

mFluor Violet 500 SE

NBP1-76768MFV500

mFluor Violet 610 SE

NBP1-76768MFV610

PerCP

NBP1-76768PCP

Forumulation

Catalog #

BSA Free

NBP1-76768

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MAVS Antibodies »

Product Summary for MAVS Antibody [DyLight 488]

Immunogen

Antibody was raised against a 17 amino acid synthetic peptide from near the center of human VISA. The immunogen is located within amino acids 130 - 180 of VISA. Amino Acid Squence: MPVQETQAPESPGENSE

Reactivity Notes

0

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for MAVS Antibody [DyLight 488]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: MAVS

Double-stranded RNA viruses are recognized in a cell type-dependent manner by the transmembrane receptor TLR3 (MIM 603029) or by the cytoplasmic RNA helicases MDA5 (MIM 606951) and RIGI (ROBO3; MIM 608630). These interactions initiate signaling pathways that differ in their initial steps but converge in the activation of the protein kinases IKKA (CHUK; MIM 600664) and IKKB (IKBKB; MIM 603258), which activate NFKB (see MIM 164011), or TBK1 (MIM 604834) and IKKE (IKBKE; MIM 605048), which activate IRF3 (MIM 603734). Activated IRF3 and NFKB induce transcription of IFNB (IFNB1; MIM 147640). For the TLR3 pathway, the intermediary molecule before the pathways converge is the cytoplasmic protein TRIF (TICAM1; MIM 607601). For RIGI, the intermediary protein is mitochondria-bound IPS1 (Sen and Sarkar, 2005).[supplied by OMIM]

Long Name

Mitochondrial Antiviral Signaling Protein

Alternate Names

Cardif, IPS-1, VISA

Gene Symbol

MAVS

Additional MAVS Products

Product Documents for MAVS Antibody [DyLight 488]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for MAVS Antibody [DyLight 488]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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