MBTPS1 Antibody (2E6)

Novus Biologicals, part of Bio-Techne | Catalog # H00008720-M07

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 2E6

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MBTPS1/SKI-1 Antibodies »

Product Specifications

Immunogen

MBTPS1 (NP_957720.1, 246 a.a. ~ 355 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. GLGHGTFVAGVIASMRECQGFAPDAELHIFRVFTNNQVSYTSWFLDAFNYAILKKIDVLNLSIGGPDFMDHPFVDKVWELTANNVIMVSAIGNDGPLYGTLNNPADQMDV

Specificity

Reacts with membrane-bound transcription factor peptidase, site 1.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for MBTPS1 Antibody (2E6)

Immunocytochemistry/ Immunofluorescence: MBTPS1 Antibody (2E6) [H00008720-M07]

Immunocytochemistry/ Immunofluorescence: MBTPS1 Antibody (2E6) [H00008720-M07]

Immunocytochemistry/Immunofluorescence: MBTPS1 Antibody (2E6) [H00008720-M07] - Analysis of monoclonal antibody to MBTPS1 on HeLa cell. Antibody concentration 10 ug/ml
ELISA: MBTPS1 Antibody (2E6) [H00008720-M07]

ELISA: MBTPS1 Antibody (2E6) [H00008720-M07]

ELISA: MBTPS1 Antibody (2E6) [H00008720-M07] - MBTPS1 Antibody (2E6) [H00008720-M07] - Detection limit for recombinant GST tagged MBTPS1 is 0.1 ng/ml as a capture antibody.

Applications for MBTPS1 Antibody (2E6)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody is reactive against recombinant protein in ELISA.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: MBTPS1/SKI-1

The encoded protein has a central role in the regulation of lipid metabolism in cells. It is a sterol-regulated subtilisin-like serine protease that cleaves ER membrane-bound sterol regulatory element-binding proteins (SREBPs), a reaction that initiates the two-step proteolytic process by which transcriptionally active fragments of SREBPs are released from the membrane for translocation to the nucleus. The gene product is an integral membrane ER protein, with the bulk located in the ER lumen. It is synthesized as an inactive preproprotein that is self-activated by an intramolecular cleavage that generates the mature protein. [provided by RefSeq]

Long Name

Membrane Bound Transcription Factor Peptidase, Site 1

Alternate Names

KIAA0091, PCSK8, S1P, SEDKF, SKI-1

Entrez Gene IDs

8720 (Human)

Gene Symbol

MBTPS1

Additional MBTPS1/SKI-1 Products

Product Documents for MBTPS1 Antibody (2E6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for MBTPS1 Antibody (2E6)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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