MCC Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-48671

Novus Biologicals, part of Bio-Techne
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NBP2-48671
NBP2-48671-25ul
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (99%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MCC Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: VQELVSALERLTKSSEIRHQQSAEFVNDLKRANSNLVAAYEKAKKKHQNKLKKLESQMMAMVERHETQVRMLKQRIALLEEENSRPHTNETS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MCC Antibody

Western Blot: MCC Antibody [NBP2-48671]

Western Blot: MCC Antibody [NBP2-48671]

Western Blot: MCC Antibody [NBP2-48671] - Analysis using Anti-MCC antibody NBP2-48671 (A) shows similar pattern to independent antibody NBP1-85885 (B).
Immunocytochemistry/ Immunofluorescence: MCC Antibody [NBP2-48671]

Immunocytochemistry/ Immunofluorescence: MCC Antibody [NBP2-48671]

Immunocytochemistry/Immunofluorescence: MCC Antibody [NBP2-48671] - Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
Immunohistochemistry-Paraffin: MCC Antibody [NBP2-48671]

Immunohistochemistry-Paraffin: MCC Antibody [NBP2-48671]

Immunohistochemistry-Paraffin: MCC Antibody [NBP2-48671] - Staining of human testis shows strong cytoplasmic positivity in subset of cells in seminiferus ducts.

Applications for MCC Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MCC

MCC is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternate Names

colorectal mutant cancer protein, DKFZp762O1615, FLJ38893, FLJ46755, MCC1, mutated in colorectal cancers, Protein MCC

Gene Symbol

MCC

Additional MCC Products

Product Documents for MCC Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MCC Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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