MCG10 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76729

Novus Biologicals, part of Bio-Techne
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NBP1-76729
NBP1-76729-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Bovine (100%), Mouse (100%). Backed by our 100% Guarantee.

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Western Blot

Cited:

Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all MCG10 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human MCG10. The immunogen is located within the last 50 amino acids of MCG10. Amino Acid Squence: AAANGSKKAERQKFSPY

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MCG10 Antibody - BSA Free

Western Blot: MCG10 AntibodyBSA Free [NBP1-76729]

Western Blot: MCG10 AntibodyBSA Free [NBP1-76729]

Western Blot: MCG10 Antibody [NBP1-76729] - HeLa cell lysate with MCG10 antibody at (A) 0.5, (B) 1 and (C) 2 u/mL.
MCG10 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: MCG10 Antibody - BSA Free [NBP1-76729] -

Immunocytochemistry/ Immunofluorescence: MCG10 Antibody - BSA Free [NBP1-76729] - Immunocytochemistry of MCG10 in HeLa cells with MCG10 antibody at 1 u/mL.
MCG10 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: MCG10 Antibody - BSA Free [NBP1-76729] -

Immunocytochemistry/ Immunofluorescence: MCG10 Antibody - BSA Free [NBP1-76729] - Immunofluorescence of MCG10 in Hela cells with MCG10 antibody at 20 ug/mL.

Applications for MCG10 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

1-20 ug/ml

Western Blot

0.5 - 2 ug/mL
Application Notes
Use in immunoprecipitation reported in scientific literature (PMID: 27302059).

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MCG10

MCG10 is a member of the KH-domain RNA-binding protein family. Proteins of this family also referred to as alpha-CPs, bind to RNA with specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. MCG10 is induced by p53 and DNA damage via two p53-responsive promoter elements. Its overexpression in transfected cells results in the suppression of cell proliferation by inducing apoptosis and cell cycle arrest in G2-M. Decreased expression of one isoform of MCG10 has been observed in many forms of lung cancer, leading to speculation that MCG10 can act as a tumor suppressor. Multiple alternatively spliced isoforms of MCG10 have been identified.

Alternate Names

alpha-CP4, alphaCP-4 protein, CBP, LIP4, LYST-interacting protein, MCG10, poly(rC) binding protein 4, poly(rC)-binding protein 4, RNA binding protein MCG10

Gene Symbol

PCBP4

UniProt

EAW65166 (Human)

Additional MCG10 Products

Product Documents for MCG10 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for MCG10 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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