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MCPH1 Antibody (5C9)

Novus Biologicals, part of Bio-Techne | Catalog # H00079648-M07

Novus Biologicals, part of Bio-Techne
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H00079648-M07

Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 5C9

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

MCPH1 (NP_078872, 399 a.a. ~ 487 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. ATSSCVTSAPEEALRCCRQAGKEDACPEGNGFSYTIEDPALPKGHDDDLTPLEGSLEEMKEAVGLKSTQNKGTTSKISNSSEGEAQSEH

Reactivity Notes

Human. Other species not tested.

Specificity

MCPH1 - microcephaly, primary autosomal recessive 1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for MCPH1 Antibody (5C9)

ELISA: MCPH1 Antibody (5C9) [H00079648-M07]

ELISA: MCPH1 Antibody (5C9) [H00079648-M07]

ELISA: MCPH1 Antibody (5C9) [H00079648-M07] - Detection limit for recombinant GST tagged MCPH1 is approximately 0.03ng/ml as a capture antibody.

Applications for MCPH1 Antibody (5C9)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: MCPH1

MCPH-1 was identified in a screen for negative regulators of hTERT (human telomerase) expression. It has been implicated in chromosome condensation and DNA damage induced cellular responses. It may play a role in neurogenesis and regulation of the size of the cerebral cortex. Defects in MCPH1 are the cause of primary microcephaly 1.

Long Name

Microcephalin 1

Alternate Names

BRIT1, MCT, Microcephalin

Entrez Gene IDs

79648 (Human)

Gene Symbol

MCPH1

OMIM

251200 (Human)

Additional MCPH1 Products

Product Documents for MCPH1 Antibody (5C9)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MCPH1 Antibody (5C9)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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