MD-1/LY86 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76709

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all MD-1 Antibodies »

Product Summary for MD-1/LY86 Antibody - BSA Free

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide from near the center of human MD-1. The immunogen is located within the last 50 amino acids of MD-1. Amino Acid Squence: CGRRKGEQIYYAGPV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MD-1/LY86 Antibody - BSA Free

Western Blot: MD-1/LY86 AntibodyBSA Free [NBP1-76709]

Western Blot: MD-1/LY86 AntibodyBSA Free [NBP1-76709]

Western Blot: MD-1/LY86 Antibody [NBP1-76709] - Daudi cell lysate with LY86 antibody at (A) 1 and (B) 2 ug/mL.
Immunohistochemistry-Paraffin: MD-1/LY86 Antibody - BSA Free [NBP1-76709]

Immunohistochemistry-Paraffin: MD-1/LY86 Antibody - BSA Free [NBP1-76709]

Immunohistochemistry-Paraffin: MD-1/LY86 Antibody [NBP1-76709] - Human spleen tissue with LY86 antibody at 2.5 ug/ml.

Applications for MD-1/LY86 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

1-2 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MD-1

Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD-1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.

Long Name

Myeloid Differentiation Protein 1/Lymphocyte Antigen 86

Alternate Names

LY86, MD1

Gene Symbol

LY86

UniProt

NP_004262 (Human)

Additional MD-1 Products

Product Documents for MD-1/LY86 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MD-1/LY86 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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